Primary cilia are microtubule-based sensory organelles necessary for efficient transduction of extracellular cues.To initiate cilia formation, ciliary vesicles (CVs) are transported to the vicinity of the centrosome Glass where they dock to the distal end of the mother centriole and fuse to initiate cilium assembly.However, to this date, the early
PATIENTS WITH METASTATIC CANCER OF UNKNOWN PRIMARY SITE: DIAGNOSTIC WORKUP AND THERAPEUTIC MANAGEMENT
PATIENTS WITH METASTATIC CANCER OF UNKNOWN PRIMARY SITE: DIAGNOSTIC WORKUP AND THERAPEUTIC MANAGEMENT Majeed H Alwan FRCS, FACS, Gastrointestinal and General Surgeon, Wellington Hospital, Wellington, New Zealand Abstract Metastatic Cancer of Unknown Primary site (CUP) accounts for about 4% of all cancer patients and is therefore one of the 10 most
Murine vaginal secretory responses to a male volatile chemical messenger
Abstract Many species use chemical messengers to communicate a remarkable range of information.Mice appear to make particular use of chemical messengers, including effects on estrous cycling and initiation, pregnancy, aggression, stress and of course attraction.Behavioral studies have helped identify several candidate messengers, or pheromones, tha
Mesoangioblasts from Facioscapulohumeral Muscular Dystrophy Display in Vivo a Variable Myogenic Ability Predictable by their in Vitro Behavior
Facioscapulohumeral muscular dystrophy (FSHD) is the third most frequent inherited myopathy.We previously demonstrated that mesoangioblasts can be efficiently isolated from FSHD muscles, although their differentiation ability into skeletal muscle was variably impaired.This correlates with overall disease severity and degree of histopathologic abnor
The single-dose Janssen Ad26.COV2.S COVID-19 vaccine elicited robust and persistent anti-spike IgG antibody responses in a 12-month Ugandan cohort
IntroductionThe study investigation examined the immune response to the Janssen Ad26.COV2.S COVID-19 vaccine within a Ugandan cohort, specifically targeting antibodies directed against spike (S) and nucleocapsid (N) proteins.We aimed to examine the durability and robustness of the induced antibody response while also assessing occurrences of breakt